RESEARCH DIETS

モルモット用 コレステロール添加飼料

脂肪量やコレステロール量、各種原料の指定など、オーダーメイドが可能。
配合例の詳細についてはこちらまでお問合せください。

研究領域

動脈硬化・脂質代謝、 その他

形状

固形 (細い直径3/16インチのペレットにて作製します）・粉末

使用上の注意

脂肪含有量や配合内容によって推奨保存温度が異なります。
詳しくはこちらまでお問合せください。

対応動物種

モルモット

参考論文・資料

論文など参考情報については、お気軽にこちらよりお申し付けください。

リサーチダイエット社ホームページより

動脈硬化のレビューはこちら　PDF

メタボリックシンドロームのレビューはこちら　PDF

Updated: May 08, 2012

  1. Abdel-Fattah, G. et al. Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. J. Lipid Res. 36: 1188-1198, 1995.
  2. Conde, K., et al. Hypocholesterolemic actions of atorvastatin are associated with alterations on hepatic cholesterol metabolism and lipoprotein composition in the guinea pig. J. Lipid Res. 37: 2372-2382, 1996.
  3. Fernandez, M.L. et al. Regulation of guinea pig plasma low density lipoprotein kinetics by dietary fat saturation. J. Lipid Res. 33: 97-109, 1992.
  4. Fernandez, M.L. Dietary fiber and mechanisms of plasma LDL lowering. J. Lipid Res. 36: 2394-2404. 1995.
  5. Lin, E. C. K., M. L. Fernandez, M.A. Tosca, and D. J. McNamara. Regulation of hepatic LDL metabolism in the guinea pig by dietary fat and cholesterol. J. Lipid Res. 35: 446-457, 1994.
  6. Ramjiganesh, T. et al. 2002. Corn Fiber Oil Lowers Plasma Cholesterol by Altering Hepatic Cholesterol Metabolism and Up-Regulating LDL Receptors in Guinea Pigs. J. Nutr. 132: 335–340, 2002.
  7. Roy , S. et al. Gender and hormonal status affect the regulation of hepatic cholesterol 7-hydroxylase activity and mRNA abundance by dietary soluble fiber in the guinea pig. Atherosclerosis 163 (2002) 29–37.
  8. Vergara-Jimenez, M., K. Conde, S. K. Erickson and M. L. Fernandez. Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat–sucrose diets: alterations on hepatic cholesterol metabolism. J. Lipid Res. 39: 1455-1465, 1998.
  9. West, K. L. et al. 1-[4-[4[(4R,5R)-3,3-Dibutyl-7-(dimethylamino)-2,3,4,5- tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza-1-azoniabicyclo[2.2.2]octane Methanesulfonate (SC-435), an Ileal Apical Sodium- Codependent Bile Acid Transporter Inhibitor Alters Hepatic Cholesterol Metabolism and Lowers Plasma Low-Density Lipoprotein-Cholesterol Concentrations in Guinea Pigs. JPET 303:293–299, 2002.
  10. Conde, K. et al. Hypocholesterolemic Effects of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors in the Guinea Pig. Biochemical Pharmacology, Vol. 58, pp. 1209–1219, 1999.
  11. Fernandez, M. L., E. C. K. Lin, and D. J. McNamara. Differential effects of saturated fatty acids on low density lipoprotein metabolism in the guinea pig. J. Lipid Res. 33: 1833-1842, 1992.
  12. Fernandez, M. L. et al. Psyllium reduces plasma LDL in guinea pigs by altering hepatic cholesterol homeostasis. J. Lipid Res. 36: 1128-1138, 1995.
  13. Fernandez, M. L. et al. Gender differences in response to dietary soluble fiber in guinea pigs: effects of pectin, guar gum, and psyllium. J. Lipid Res. 36: 2191-2202, 1995.
  14. Fernandez, M. L. Guinea Pigs as Models for Cholesterol and Lipoprotein Metabolism. J. Nutr. 131: 10–20, 2001.
  15. Ramjiganesh, T. et al. Corn husk oil lowers plasma LDL cholesterol concentrations by decreasing cholesterol absorption and altering hepatic cholesterol metabolism in guinea pigs. J. Nutr. Biochem. 11:358 –366, 2000.
  16. Romero, A. L. et al. The Seeds from Plantago ovata Lower Plasma Lipids by Altering Hepatic and Bile Acid Metabolism in Guinea Pigs. J. Nutr. 132: 1194–1198, 2002.
  17. Roy , S., S. Vega-Lopez and M. L. Fernandez. Gender and Hormonal Status Affect the Hypolipidemic Mechanisms of Dietary Soluble Fiber in Guinea Pigs. J. Nutr. 130: 600–607, 2000.
  18. West, K. L. et al. SC-435, an ileal apical sodium co-dependent bile acid transporter (ASBT) inhibitor lowers plasma cholesterol and reduces atherosclerosis in guinea pigs. Atherosclerosis 171 (2003) 201–210.
  19. Zern, T. L., K. L. West and M. L. Fernandez. Grape Polyphenols Decrease Plasma Triglycerides and Cholesterol Accumulation in the Aorta of Ovariectomized Guinea Pigs. J. Nutr. 133: 2268–2272, 2003.
  20. Fernandez, M. L. et al. Hamsters and Guinea Pigs Differ in Their Plasma Lipoprotein Cholesterol Distribution when Fed Diets Varying in Animal Protein, Soluble Fiber, or Cholesterol Content. J. Nutr. 129: 1323–1332, 1999.
  21. Fernandez ML, Wilson TA, Conde K, Vergara-Jiminez M & Nicolosi RJ. Hamsters and Guinea Pigs Differ in Their Plasma Lipoprotein Cholesterol Distribution when Fed Diets Varying in Animal Protein, Soluble Fiber, or Cholesterol Content. American Society for Nutritional Sciences. 1999; 0022:1323-1331
  22. Vergara-Jiminez M, Conde K, Erickson SK , Fernandez ML. Hypolipidemic mechanisms of pectin and psyllium in guinea pigs fed high fat-sucrose diets: alterations on hepatic cholesterol metabolism. Journal of Lipid Research. 1998; 39:1455-1465
  23. Dworakowski R, Dworakowska D, Kocic I, Wirth T, Gruchała M, Kamiński M, Petrusewicz J, Yla-Herttuala S, Rynkiewicz A. Cerivastatin and hypercholesterolemia reduce apoptosis of cardiomyocytes in guinea pig papillary muscle subjected to hypoxia/reoxygenation. Pharmacol Rep. 2006 May-Jun;58(3):420-6.
  24. Torres-Gonzalez M, Volek JS, Sharman M, Contois JH, Fernandez ML. Dietary carbohydrate and cholesterol influence the number of particles and distributions of lipoprotein subfractions in guinea pigs. J Nutr Biochem. 2006 Nov;17(11):773-9. Epub 2006 Feb 3.
  25. Torres-Gonzalez M, Shrestha S, Sharman M, Freake HC, Volek JS, Fernandez ML. Carbohydrate restriction alters hepatic cholesterol metabolism in guinea pigs fed a hypercholesterolemic diet. J Nutr. 2007 Oct;137(10):2219-23.

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